Editorial................................................................................................................................133
Přehledné články
H. Poczatková, M. Rypka, J. Veselý, L. Uherková, K. ČervenkováStruktura a aktivace proteinkinázy C (PKC)..............................................................................136
K. Javorka, M. Javorka, I. TonhajzerováMožnosti hodnotenia respiračnej sínusovej arytitmie a zvyšovania parasympatikového vplyvu na srdce.......................................................................................141
R. RokytaPatofyziologické principy neuromodulačních metod.................................................................149
R. StodůlkaNové směry neuromodulační léčby.........................................................................................153
A. Tillinger, R. Kvetňanský, O. KrižanováAdrenergické receptory a srdce: od génovej expresie po funkciu...............................................156
A. Potáčová, M. Adamcová, M. Štěrba, O. Popelová, V. GeršlRole matrixových metaloproteináz při srdečním selhání............................................................168
Různé..................................................................................................................................176
Abstrakta.............................................................................................................................181
Informace.............................................................................................................................218
Contents
Editorial..............................................................................................................................133
Reviews
H. Poczatková, M. Rypka, J. Veselý, L. Uherková, K. ČervenkováStructure and activation of proteinkinases C (PKCs)................................................................136
K. Javorka, M. Javorka, I. TonhajzerováHow to evaluate respiratory sinus arrhytmia and to enhance the parasympathetic cardiac regulation..................................................................................................................141
R. RokytaThe pathophysiological principles of neuromodulatory methods.................................................149
R. StodůlkaNew methods of neuromodulation treatment.............................................................................153
A. Tillinger, R. Kvetňanský, O. KrižanováAdrenergic receptor in the heart: from gene expression to function.............................................156
A. Potáčová, M. Adamcová, M. Štěrba, O. Popelová, V. GeršlRole of matrix metalloproteinases in heart failure.......................................................................168
Miscellaneous........................................................................................................................176
Abstracts..............................................................................................................................181
Informations...........................................................................................................................218
Editorial...............................................................................................................................89
Obsah
J. Bronský, J. Nevoral, R. PrůšaAdiponektin - marker insulinové sensitivity..............................................................................92
M. BucováProkalcitonín - prohormón, hormokín, mediátor zápalu, diagnostický a prognostikcý marker systémového zápalu..................................................................................................97
K. Javorka, M. JavorkaRespiračná sínusová arytmia - mechanizmy a fyziologický význam........................................109
H. Maxová, L. VajnerŽírné buňky a jejich úloha v procesu tkáňové remodelace.......................................................115
H. Poczatková, M. Rypka, J. Veselý, D. RiegrováProteinkináza c(PKC) a její role v metabolismu mastných kyselin a glukózy............................120
Různé...............................................................................................................................125
Editorial..............................................................................................................................89
J. Bronský, J. Nevoral, R. PrůšaAdiponectin - marker of insulin sensitivity..............................................................................92
M. BucováProcalcitonin - prohormon, hormokine, mediator of inflammation, diagnostic and prognosticmarker of systemic inflammation..........................................................................................97
K. Javorka, M. JavorkaRespiratory Sinus arrhytmia - mechanisms and physiological role..........................................109
H. Maxová, L. VajnerMast cells and their role in tissue remodeling.......................................................................115
H. Poczatková, M. Rypka, J. Veselý, D. RiegrováThe role of PKC in the metabolism of free fatty acids and glucose..........................................120
Miscellaneous...................................................................................................................125
Editorial...................................................................................................................................45
I. BéderTvorba, prúdenie a zloženie pľúcnej lymfy...................................................................................48
J. Graban, A. KohútMechanizmy apoptózy T-lymfocytov..........................................................................................54
M. M. Haluzík, M. Haluzíktuková tkáň a inzulínová rezistence: experimentální využití transgenních myších modelů..................62
J. Slavíková, J. Kuncová, Ml Chottová-Dvořáková, J. ReischigNeadrenergní necholinergní nervová regulace srdeční činnosti: morfologie a funkcepeptidergní inervace srdce savců...............................................................................................70
RůznéVzpomínka na J. Axelroda, nositele Nobelovy ceny za fyziologii nebo medicínu za rok 1970, a jehoodkaz pro dnešní vědu.............................................................................................................78
Vzpomínka - prof. MUDr. Olga Benešová, DrSc. ........................................................................81
Zdeněk Rychter osmdesátníkem (jak jsem ho poznal)..................................................................82
Zprávy...................................................................................................................................83
Editorial.................................................................................................................................45
I. BéderFormation, circulation and composition of pulmonary lymph.........................................................48
J. Graban, A. KohútT-lymphocytes apoptosis mechanisms......................................................................................54
M. M. Haluzík, M. HaluzíkAdipose tissue and insulin resistance: experimental utilization transgenic mice models......................62
J. Slavíková, J. Kuncová, M. Chottová-Dvořáková, J. ReischigNonadrenergic noncholinergic regulation of the cardiac performance: morphology and functionof the peptidergic innervation of the mammalian heart.................................................................70
Miscellaneous
A tribute to J. Axelrod, the Nobel prize laureate in physiology or medicine in 1970,and his legacy to current science..............................................................................................78
A recollection - Prof. MUDr. Olga Benešová, DrSc......................................................................81
Zdeněk Rychter turning 80 (as i knew him)................................................................................82
News....................................................................................................................................83
Editiorial.....................................................................................................................................1
V. Cucak, A. KohútÚloha repraračných génov pri pľúcnom karcinóme...........................................................................4
S. Hynie, V. Klenerová, S. ŠtípekLaureáti Nobelovy ceny za fyziologii nebo lékařství, a chemii za rok 2004;příležitost k ohlédnutíse za některými objevy v přenosu signálů.....................................................................................11
R. Lichnovská, S. Gwozdziewiczová, J. HřebíčekLeptin a inzulinová rezistence......................................................................................................17
S. Reiniš, R. F. Holub, P. SmrzKvantová hypotéza činnosti mozku a vědomí................................................................................26
Š. Vaculín, R. RokytaAutomutilace jako projev spontánní neuroapitcké bolesti u zvířat.....................................................32
Zprávy....................................................................................................................................37
Rejstříky..................................................................................................................................42
Editorial.....................................................................................................................................1
Content
V. Cucak, A. KohútThe role of repair genes in lung carcinoma......................................................................................4
S. Hynie, V. Klenerová, S. ŠtípekLaureates of the Nobel Prize for physiologz or medicine and chemistry for 2004;an opportunity to have a look at some discoveries in signal transmission...........................................11
R. Lichnovská, S. Gwozdziewiczová, J. HřebíčekLeptin and insulin resistance.........................................................................................................17
S. Reiniš, R. F. Holub, P. SmrzQuantum hypothesis of brain funcitoning and consciousness............................................................26
Š. Vaculín, R. RokytaSelfmutilation in animals as a symptom of spontaneous neuropathic pain...........................................32
News.........................................................................................................................................37
Indexes......................................................................................................................................42
